Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Polymerase basic protein 2' and Ligand = 'BDBM50050700'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Polymerase basic protein 2 (Influenza A virus (strain A/Puerto Rico/8/1934 H1N...)	BDBM50050700 (CHEMBL3317985) Show SMILES Fc1cnc(nc1N[C@H]1CCC[C@H](C1)NC(=O)CN1CCOCC1)-c1c[nH]c2ncc(Cl)cc12 |r| Show InChI InChI=1S/C23H27ClFN7O2/c24-14-8-17-18(11-27-21(17)26-10-14)22-28-12-19(25)23(31-22)30-16-3-1-2-15(9-16)29-20(33)13-32-4-6-34-7-5-32/h8,10-12,15-16H,1-7,9,13H2,(H,26,27)(H,29,33)(H,28,30,31)/t15-,16+/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	200	n/a	n/a	n/a	n/a	n/a
Vertex Pharmaceuticals Inc. Curated by ChEMBL					Assay Description Binding affinity to influenza A virus (A/Puerto Rico/8/1934(H1N1)) PB2 by competition binding fluorescence polarization (FP) assay				J Med Chem 57: 6668-78 (2014) Article DOI: 10.1021/jm5007275 BindingDB Entry DOI: 10.7270/Q2R21316
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