Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Polymerase basic protein 2' and Ligand = 'BDBM50050722'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Polymerase basic protein 2 (Influenza A virus (strain A/Puerto Rico/8/1934 H1N...)	BDBM50050722 (CHEMBL3317974) Show SMILES CS(=O)(=O)N1CCCC[C@@H]1CNc1nc(ncc1F)-c1c[nH]c2ncc(Cl)cc12 |r| Show InChI InChI=1S/C18H20ClFN6O2S/c1-29(27,28)26-5-3-2-4-12(26)8-22-18-15(20)10-24-17(25-18)14-9-23-16-13(14)6-11(19)7-21-16/h6-7,9-10,12H,2-5,8H2,1H3,(H,21,23)(H,22,24,25)/t12-/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	100	n/a	n/a	n/a	n/a	n/a
Vertex Pharmaceuticals Inc. Curated by ChEMBL					Assay Description Binding affinity to influenza A virus (A/Puerto Rico/8/1934(H1N1)) PB2 by competition binding fluorescence polarization (FP) assay				J Med Chem 57: 6668-78 (2014) Article DOI: 10.1021/jm5007275 BindingDB Entry DOI: 10.7270/Q2R21316
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