Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1' and Ligand = 'BDBM50326988'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1 (Mus musculus)	BDBM50326988 (3-(3-{[2-(3,4-Dimethoxy-phenyl)-ethyl]-methyl-amin...) Show SMILES COc1ccc(CCN(C)CCCN2CCc3cc(OC)c(OC)cc3CC2=O)cc1OC Show InChI InChI=1S/C26H36N2O5/c1-27(13-9-19-7-8-22(30-2)23(15-19)31-3)11-6-12-28-14-10-20-16-24(32-4)25(33-5)17-21(20)18-26(28)29/h7-8,15-17H,6,9-14,18H2,1-5H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	n/a	n/a	1.68E+4	n/a	n/a	n/a	n/a
Laboratory of Design, Synthesis, and Study of Biologically Active Heterocycles (HeteroBioLab) Curated by ChEMBL					Assay Description Blockade of mouse HCN1 expressed in HEK293 cells at -120 f-current amplitude by patch-clamp electrophysiological assay				J Med Chem 53: 6773-7 (2010) Article DOI: 10.1021/jm1006758 BindingDB Entry DOI: 10.7270/Q2T43T9J
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