Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1' and Ligand = 'BDBM50419078'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1 (Homo sapiens (Human))	BDBM50419078 (CHEMBL1823667) Show SMILES CN1CCN(CC1)C1(CNC(=O)c2ccccc2OCc2ccccc2)Cc2ccccc2C1 Show InChI InChI=1S/C29H33N3O2/c1-31-15-17-32(18-16-31)29(19-24-11-5-6-12-25(24)20-29)22-30-28(33)26-13-7-8-14-27(26)34-21-23-9-3-2-4-10-23/h2-14H,15-22H2,1H3,(H,30,33)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	631	n/a	n/a	n/a	n/a	n/a	n/a
Johnson& Johnson Pharmaceutical Research& Development Curated by ChEMBL					Assay Description Inhibition of human HCN1 heterologously expressed in HEK-293 cells after 30 mins by VIPR assay				Bioorg Med Chem Lett 21: 5197-201 (2011) Article DOI: 10.1016/j.bmcl.2011.07.051 BindingDB Entry DOI: 10.7270/Q2PV6MNP
					More data for this Ligand-Target Pair