Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2' and Ligand = 'BDBM50326991'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2 (Mus musculus)	BDBM50326991 (3-((E)-4-((3,4-dimethoxyphenethyl)(methyl)amino)bu...) Show SMILES COc1ccc(CCN(C)C\C=C\CN2C=Cc3cc(OC)c(OC)cc3CC2=O)cc1OC |c:15| Show InChI InChI=1S/C27H34N2O5/c1-28(14-10-20-8-9-23(31-2)24(16-20)32-3)12-6-7-13-29-15-11-21-17-25(33-4)26(34-5)18-22(21)19-27(29)30/h6-9,11,15-18H,10,12-14,19H2,1-5H3/b7-6+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	1.72E+4	n/a	n/a	n/a	n/a
Laboratory of Design, Synthesis, and Study of Biologically Active Heterocycles (HeteroBioLab) Curated by ChEMBL					Assay Description Blockade of mouse HCN2 expressed in HEK293 cells at -120 f-current amplitude by patch-clamp electrophysiological assay				J Med Chem 53: 6773-7 (2010) Article DOI: 10.1021/jm1006758 BindingDB Entry DOI: 10.7270/Q2T43T9J
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