Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4' and Ligand = 'BDBM50419059'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4 (Homo sapiens (Human))	BDBM50419059 (CHEMBL1823672) Show SMILES CN1CCN(CC1)C1(CNC(=O)c2ccccc2O)Cc2ccccc2C1 Show InChI InChI=1S/C22H27N3O2/c1-24-10-12-25(13-11-24)22(14-17-6-2-3-7-18(17)15-22)16-23-21(27)19-8-4-5-9-20(19)26/h2-9,26H,10-16H2,1H3,(H,23,27)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>2.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Johnson& Johnson Pharmaceutical Research& Development Curated by ChEMBL					Assay Description Inhibition of human HCN4 heterologously expressed in HEK-293 cells after 30 mins by VIPR assay				Bioorg Med Chem Lett 21: 5197-201 (2011) Article DOI: 10.1016/j.bmcl.2011.07.051 BindingDB Entry DOI: 10.7270/Q2PV6MNP
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