Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Potassium voltage-gated channel subfamily H member 2' and Ligand = 'BDBM247046'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human))	BDBM247046 (2-((1R,3aR,6S, 7R,7aS)-7-((E)- 2- (2'-cyano-[3...) Show SMILES C[C@H]1OC(=O)[C@]2(CC(N)=O)CC(F)(F)[C@@H](C)[C@H](\C=C\c3ccc(cn3)-c3cccnc3C#N)[C@H]12 |r| Show InChI InChI=1S/C25H24F2N4O3/c1-14-18(22-15(2)34-23(33)24(22,10-21(29)32)13-25(14,26)27)8-7-17-6-5-16(12-31-17)19-4-3-9-30-20(19)11-28/h3-9,12,14-15,18,22H,10,13H2,1-2H3,(H2,29,32)/b8-7+/t14-,15+,18-,22-,24+/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2.19E+4	n/a	n/a	n/a	n/a	7.4	25
Merck Sharp & Dohme Corp. US Patent					Assay Description Drug cardiac arrhythmia is an important safety concern for pharmaceutical development and health regulatory authorities. Blockade of heterologously-e...				US Patent US9701669 (2017) BindingDB Entry DOI: 10.7270/Q2PC34DS
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