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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Potassium voltage-gated channel subfamily H member 2' and Ligand = 'BDBM50214368'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Potassium voltage-gated channel subfamily H member 2


(Homo sapiens (Human))
BDBM50214368
PNG
(24-{[(3-{[2-(4-methanesulfonamidophenoxy)ethyl][2-...)
Show SMILES CC1(C)C2=C3C=C4C(CC[N+]5=C4C(C)(C)c4cc(ccc54)S([O-])(=O)=O)OC3CCN2c2ccc(CC(=O)NCCCN(CCOc3ccc(NS(C)(=O)=O)cc3)CCc3ccc(NS(C)(=O)=O)cc3)cc12 |w:26.28,7.27,c:3,5,10|
Show InChI InChI=1S/C52H62N6O10S3/c1-51(2)42-30-35(10-18-44(42)57-26-21-46-40(49(51)57)33-41-47(68-46)22-27-58-45-19-17-39(71(64,65)66)32-43(45)52(3,4)50(41)58)31-48(59)53-23-7-24-56(25-20-34-8-11-36(12-9-34)54-69(5,60)61)28-29-67-38-15-13-37(14-16-38)55-70(6,62)63/h8-19,30,32-33,46-47,54-55H,7,20-29,31H2,1-6H3,(H-,53,59,64,65,66)
PDB
MMDB

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PC cid
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Article
PubMed
160n/an/an/an/an/an/an/an/a



Pfizer Global Research and Development

Curated by ChEMBL


Assay Description
Displacement of [3H]dofetilide from hERG expressed in HEK293 cells by SPA


J Med Chem 50: 2931-41 (2007)


Article DOI: 10.1021/jm0700565
BindingDB Entry DOI: 10.7270/Q2736RR2
More data for this
Ligand-Target Pair