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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Potassium voltage-gated channel subfamily H member 2' and Ligand = 'BDBM50275710'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Potassium voltage-gated channel subfamily H member 2


(Homo sapiens (Human))
BDBM50275710
PNG
(CHEMBL486738 | N-(2-aminophenyl)-6-(2,3-dihydro-1H...)
Show SMILES Nc1ccccc1NC(=O)c1ccc(nc1)N1CCC2(CC1)CNCc1ccccc21
Show InChI InChI=1S/C25H27N5O/c26-21-7-3-4-8-22(21)29-24(31)19-9-10-23(28-16-19)30-13-11-25(12-14-30)17-27-15-18-5-1-2-6-20(18)25/h1-10,16,27H,11-15,17,26H2,(H,29,31)
PDB
MMDB

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Article
PubMed
1.76E+3n/an/an/an/an/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
Displacement of [35S]MK499 from human ERG expressed in HEK293 cells


Bioorg Med Chem Lett 18: 6104-9 (2008)


Article DOI: 10.1016/j.bmcl.2008.10.052
BindingDB Entry DOI: 10.7270/Q23R0SQ2
More data for this
Ligand-Target Pair