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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Potassium voltage-gated channel subfamily H member 2' and Ligand = 'BDBM50343365'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Potassium voltage-gated channel subfamily H member 2


(Homo sapiens (Human))
BDBM50343365
PNG
(4-[2,4-Dichloro-6-(4,4,4-trifluoro-butoxy)-phenyl]...)
Show SMILES Cc1cc(nc(N)n1)-c1c(Cl)cc(Cl)cc1OCCCC(F)(F)F
Show InChI InChI=1S/C15H14Cl2F3N3O/c1-8-5-11(23-14(21)22-8)13-10(17)6-9(16)7-12(13)24-4-2-3-15(18,19)20/h5-7H,2-4H2,1H3,(H2,21,22,23)
PDB
MMDB

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PC cid
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Article
PubMed
1.16E+4n/an/an/an/an/an/an/an/a



Pfizer Inc.

Curated by ChEMBL


Assay Description
Displacement of [3H]dofetilide from human ERG channel expressed in HEK293 cells


J Med Chem 54: 3368-85 (2011)


Article DOI: 10.1021/jm200128m
BindingDB Entry DOI: 10.7270/Q2Z320M5
More data for this
Ligand-Target Pair