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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Potassium voltage-gated channel subfamily H member 2' and Ligand = 'BDBM50359189'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Potassium voltage-gated channel subfamily H member 2


(Homo sapiens (Human))
BDBM50359189
PNG
(CHEMBL1923126)
Show SMILES Fc1cc2C(=O)O[C@@]3(CCNC[C@@H]3C(=O)N(Cc3cccc(c3Cl)C(F)(F)F)C3CC3)c2cc1F |r|
Show InChI InChI=1S/C24H20ClF5N2O3/c25-20-12(2-1-3-15(20)24(28,29)30)11-32(13-4-5-13)21(33)17-10-31-7-6-23(17)16-9-19(27)18(26)8-14(16)22(34)35-23/h1-3,8-9,13,17,31H,4-7,10-11H2/t17-,23+/m1/s1
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PC cid
PC sid
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Article
PubMed
1.30E+4n/an/an/an/an/an/an/an/a



Merck Frosst Centre for Therapeutic Research

Curated by ChEMBL


Assay Description
Inhibition of human ERG


Bioorg Med Chem Lett 21: 7399-404 (2011)


Article DOI: 10.1016/j.bmcl.2011.10.013
BindingDB Entry DOI: 10.7270/Q2PC32SW
More data for this
Ligand-Target Pair