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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Potassium voltage-gated channel subfamily H member 2' and Ligand = 'BDBM50402400'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Potassium voltage-gated channel subfamily H member 2


(Homo sapiens (Human))
BDBM50402400
PNG
(CHEMBL2207733)
Show SMILES Cc1ccnc2nc(Oc3ccc(CN4CCCCC4)cc3)sc12
Show InChI InChI=1S/C19H21N3OS/c1-14-9-10-20-18-17(14)24-19(21-18)23-16-7-5-15(6-8-16)13-22-11-3-2-4-12-22/h5-10H,2-4,11-13H2,1H3
PDB
MMDB

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PC cid
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Article
PubMed
n/an/a 8.10E+3n/an/an/an/an/an/a



Janssen Research& Development LLC

Curated by ChEMBL


Assay Description
Inhibition of dofetilide binding to human ERG by patch clamp assay


Bioorg Med Chem Lett 22: 7504-11 (2012)


Article DOI: 10.1016/j.bmcl.2012.10.036
BindingDB Entry DOI: 10.7270/Q2ZG6TDQ
More data for this
Ligand-Target Pair