Compile Data Set for Download or QSAR

Found 3 hits Enz. Inhib. hit(s) with Target = 'Progesterone receptor' and Ligand = 'BDBM50062418'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Progesterone receptor (Homo sapiens (Human))	BDBM50062418 (5-(6-Bromo-pyridin-3-yl)-2,2,4-trimethyl-2,5-dihyd...) Show SMILES CC1=CC(C)(C)Nc2ccc3-c4ccccc4OC(c4ccc(Br)nc4)c3c12 |t:1| Show InChI InChI=1S/C24H21BrN2O/c1-14-12-24(2,3)27-18-10-9-17-16-6-4-5-7-19(16)28-23(22(17)21(14)18)15-8-11-20(25)26-13-15/h4-13,23,27H,1-3H3	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	3.90	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Ligand Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description The binding affinity of the compound was determined on Human progesterone receptor (hPR-A) using progesterone as radioligand.				J Med Chem 41: 291-302 (1998) Article DOI: 10.1021/jm9705768 BindingDB Entry DOI: 10.7270/Q29W0DMD
					More data for this Ligand-Target Pair
Progesterone receptor (Homo sapiens (Human))	BDBM50062418 (5-(6-Bromo-pyridin-3-yl)-2,2,4-trimethyl-2,5-dihyd...) Show SMILES CC1=CC(C)(C)Nc2ccc3-c4ccccc4OC(c4ccc(Br)nc4)c3c12 |t:1| Show InChI InChI=1S/C24H21BrN2O/c1-14-12-24(2,3)27-18-10-9-17-16-6-4-5-7-19(16)28-23(22(17)21(14)18)15-8-11-20(25)26-13-15/h4-13,23,27H,1-3H3	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	54	n/a	n/a	n/a	n/a	n/a	n/a
Ligand Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description Antagonistic activity was determined in Human progesterone receptor(hPR) of CV-1 cells in cotransfection assay.				J Med Chem 41: 291-302 (1998) Article DOI: 10.1021/jm9705768 BindingDB Entry DOI: 10.7270/Q29W0DMD
					More data for this Ligand-Target Pair
Progesterone receptor (Homo sapiens (Human))	BDBM50062418 (5-(6-Bromo-pyridin-3-yl)-2,2,4-trimethyl-2,5-dihyd...) Show SMILES CC1=CC(C)(C)Nc2ccc3-c4ccccc4OC(c4ccc(Br)nc4)c3c12 |t:1| Show InChI InChI=1S/C24H21BrN2O/c1-14-12-24(2,3)27-18-10-9-17-16-6-4-5-7-19(16)28-23(22(17)21(14)18)15-8-11-20(25)26-13-15/h4-13,23,27H,1-3H3	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	3.90E+3	n/a	n/a	n/a	n/a
Ligand Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description Agonistic activity to the human progesterone receptor(hPR)assayed in CV-1 cells in cotransfection assay.				J Med Chem 41: 291-302 (1998) Article DOI: 10.1021/jm9705768 BindingDB Entry DOI: 10.7270/Q29W0DMD
					More data for this Ligand-Target Pair