Compile Data Set for Download or QSAR

Found 3 hits Enz. Inhib. hit(s) with Target = 'Progesterone receptor' and Ligand = 'BDBM50062424'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Progesterone receptor (Homo sapiens (Human))	BDBM50062424 (1-[4-(2,2,4-Trimethyl-2,5-dihydro-1H-6-oxa-1-aza-c...) Show SMILES CC(=O)c1ccc(cc1)C1Oc2ccccc2-c2ccc3NC(C)(C)C=C(C)c3c12 |t:27| Show InChI InChI=1S/C27H25NO2/c1-16-15-27(3,4)28-22-14-13-21-20-7-5-6-8-23(20)30-26(25(21)24(16)22)19-11-9-18(10-12-19)17(2)29/h5-15,26,28H,1-4H3	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	8.80	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Ligand Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description The binding affinity of the compound was determined on Human progesterone receptor (hPR-A) using progesterone as radioligand.				J Med Chem 41: 291-302 (1998) Article DOI: 10.1021/jm9705768 BindingDB Entry DOI: 10.7270/Q29W0DMD
					More data for this Ligand-Target Pair
Progesterone receptor (Homo sapiens (Human))	BDBM50062424 (1-[4-(2,2,4-Trimethyl-2,5-dihydro-1H-6-oxa-1-aza-c...) Show SMILES CC(=O)c1ccc(cc1)C1Oc2ccccc2-c2ccc3NC(C)(C)C=C(C)c3c12 |t:27| Show InChI InChI=1S/C27H25NO2/c1-16-15-27(3,4)28-22-14-13-21-20-7-5-6-8-23(20)30-26(25(21)24(16)22)19-11-9-18(10-12-19)17(2)29/h5-15,26,28H,1-4H3	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	132	n/a	n/a	n/a	n/a	n/a	n/a
Ligand Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description Antagonistic activity was determined in Human progesterone receptor(hPR) of CV-1 cells in cotransfection assay.				J Med Chem 41: 291-302 (1998) Article DOI: 10.1021/jm9705768 BindingDB Entry DOI: 10.7270/Q29W0DMD
					More data for this Ligand-Target Pair
Progesterone receptor (Homo sapiens (Human))	BDBM50062424 (1-[4-(2,2,4-Trimethyl-2,5-dihydro-1H-6-oxa-1-aza-c...) Show SMILES CC(=O)c1ccc(cc1)C1Oc2ccccc2-c2ccc3NC(C)(C)C=C(C)c3c12 |t:27| Show InChI InChI=1S/C27H25NO2/c1-16-15-27(3,4)28-22-14-13-21-20-7-5-6-8-23(20)30-26(25(21)24(16)22)19-11-9-18(10-12-19)17(2)29/h5-15,26,28H,1-4H3	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a
Ligand Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description Agonistic activity to the human progesterone receptor(hPR)assayed in CV-1 cells in cotransfection assay.				J Med Chem 41: 291-302 (1998) Article DOI: 10.1021/jm9705768 BindingDB Entry DOI: 10.7270/Q29W0DMD
					More data for this Ligand-Target Pair