BindingDB PrimarySearch

Found 5 hits Enz. Inhib. hit(s) with Target = 'Progesterone receptor' and Ligand = 'BDBM50067670'
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Progesterone receptor (Homo sapiens (Human))	BDBM50067670 (5-[1-(3-Fluoro-phenyl)-meth-(Z)-ylidene]-2,2,4-tri...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.830	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Ligand Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description Binding affinity against human progesterone receptor				J Med Chem 41: 4354-9 (1998) Article DOI: 10.1021/jm980366a BindingDB Entry DOI: 10.7270/Q2V40TB5
Ligand Pharmaceuticals, Inc. Curated by ChEMBL					More data for this Ligand-Target Pair
Progesterone receptor (Homo sapiens (Human))	BDBM50067670 (5-[1-(3-Fluoro-phenyl)-meth-(Z)-ylidene]-2,2,4-tri...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.830	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Ligand Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description Compound was evaluated for its binding affinity against baculovirus expressed Progesterone receptor				J Med Chem 42: 1466-72 (1999) Article DOI: 10.1021/jm980723h BindingDB Entry DOI: 10.7270/Q2NK3FQ9
Ligand Pharmaceuticals, Inc. Curated by ChEMBL					More data for this Ligand-Target Pair
Progesterone receptor (Homo sapiens (Human))	BDBM50067670 (5-[1-(3-Fluoro-phenyl)-meth-(Z)-ylidene]-2,2,4-tri...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	7.60	n/a	n/a	n/a	n/a
Ligand Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description Compound was tested for agonistic activity by cotransfection assay against human Progesterone receptor in CV-1 cells				J Med Chem 42: 1466-72 (1999) Article DOI: 10.1021/jm980723h BindingDB Entry DOI: 10.7270/Q2NK3FQ9
Ligand Pharmaceuticals, Inc. Curated by ChEMBL					More data for this Ligand-Target Pair
Progesterone receptor (Homo sapiens (Human))	BDBM50067670 (5-[1-(3-Fluoro-phenyl)-meth-(Z)-ylidene]-2,2,4-tri...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	7.60	n/a	n/a	n/a	n/a
Ligand Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description Effective concentration (EC50) against human progesterone receptor expressed in CV-1 cell				J Med Chem 41: 4354-9 (1998) Article DOI: 10.1021/jm980366a BindingDB Entry DOI: 10.7270/Q2V40TB5
Ligand Pharmaceuticals, Inc. Curated by ChEMBL					More data for this Ligand-Target Pair
Progesterone receptor (Homo sapiens (Human))	BDBM50067670 (5-[1-(3-Fluoro-phenyl)-meth-(Z)-ylidene]-2,2,4-tri...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	51	n/a	n/a	n/a	n/a
Ligand Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description Agonistic activity by cotransfection assay against human Progesterone receptor in T47D cells				J Med Chem 42: 1466-72 (1999) Article DOI: 10.1021/jm980723h BindingDB Entry DOI: 10.7270/Q2NK3FQ9
Ligand Pharmaceuticals, Inc. Curated by ChEMBL					More data for this Ligand-Target Pair