new BindingDB logo
myBDB logout
Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Progesterone receptor' and Ligand = 'BDBM50072018'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Progesterone receptor


(Homo sapiens (Human))
BDBM50072018
PNG
(5,8-difluoro-2,2,4-trimethyl-2,10-dihydro-1H-inden...)
Show SMILES CC1=CC(C)(C)Nc2cc3Cc4cc(F)ccc4-c3c(F)c12 |t:1|
Show InChI InChI=1S/C19H17F2N/c1-10-9-19(2,3)22-15-8-12-6-11-7-13(20)4-5-14(11)17(12)18(21)16(10)15/h4-5,7-9,22H,6H2,1-3H3
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
PubMed
1.5n/an/an/an/an/an/an/an/a



Ligand Pharmaceuticals

Curated by ChEMBL


Assay Description
Antagonist activity against human progesterone receptor B (hPR-B) in cotransfected CV-1 cells


Bioorg Med Chem Lett 8: 2731-6 (1999)


BindingDB Entry DOI: 10.7270/Q2QF8S1M
More data for this
Ligand-Target Pair
Progesterone receptor


(Homo sapiens (Human))
BDBM50072018
PNG
(5,8-difluoro-2,2,4-trimethyl-2,10-dihydro-1H-inden...)
Show SMILES CC1=CC(C)(C)Nc2cc3Cc4cc(F)ccc4-c3c(F)c12 |t:1|
Show InChI InChI=1S/C19H17F2N/c1-10-9-19(2,3)22-15-8-12-6-11-7-13(20)4-5-14(11)17(12)18(21)16(10)15/h4-5,7-9,22H,6H2,1-3H3
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
PubMed
n/an/an/an/a 650n/an/an/an/a



Ligand Pharmaceuticals

Curated by ChEMBL


Assay Description
Agonistic activity against human progesterone receptor B (hPR-B) in cotransfected CV-1 cells


Bioorg Med Chem Lett 8: 2731-6 (1999)


BindingDB Entry DOI: 10.7270/Q2QF8S1M
More data for this
Ligand-Target Pair