Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Progesterone receptor (Homo sapiens (Human)) | BDBM50148732 (17-ethynyl-17beta-hydroxyestr-4-en-3-one | 17alpha...) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | DrugBank PDB Article PubMed | 1.90 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Ligand Pharmaceuticals, Inc. Curated by ChEMBL | Assay Description The binding affinity measured using baculovirus-expressed hPR-A in sf21 cells. | J Med Chem 41: 303-10 (1998) Article DOI: 10.1021/jm9705770 BindingDB Entry DOI: 10.7270/Q2RV0PC8 | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Progesterone receptor (Homo sapiens (Human)) | BDBM50148732 (17-ethynyl-17beta-hydroxyestr-4-en-3-one | 17alpha...) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | DrugBank PDB PubMed | n/a | n/a | 3.20 | n/a | n/a | n/a | n/a | n/a | n/a |
R. W. Johnson Pharmaceutical Research Institute Curated by ChEMBL | Assay Description Binding affinity against Progesterone receptor in human TE85 osteosarcoma cells was determined using (Z)-[125I]-17-alpha-(2-iodovinyl)-19-nor-testost... | J Med Chem 38: 4880-4 (1996) BindingDB Entry DOI: 10.7270/Q2KP82SZ | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Progesterone receptor (Homo sapiens (Human)) | BDBM50148732 (17-ethynyl-17beta-hydroxyestr-4-en-3-one | 17alpha...) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | DrugBank PDB Article PubMed | n/a | n/a | n/a | n/a | 2.20 | n/a | n/a | n/a | n/a |
Ligand Pharmaceuticals, Inc. Curated by ChEMBL | Assay Description Agonistic activity was measured for modulation of hPR-B (human progesterone receptor) in co-transfected CV-1 cells. | J Med Chem 41: 303-10 (1998) Article DOI: 10.1021/jm9705770 BindingDB Entry DOI: 10.7270/Q2RV0PC8 | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Progesterone receptor (Homo sapiens (Human)) | BDBM50148732 (17-ethynyl-17beta-hydroxyestr-4-en-3-one | 17alpha...) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | DrugBank PDB Article PubMed | n/a | n/a | n/a | 0.400 | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline Inc. Curated by ChEMBL | Assay Description Dissociation constant for progesterone receptor | J Med Chem 47: 3381-7 (2004) Article DOI: 10.1021/jm030640n BindingDB Entry DOI: 10.7270/Q2KP81NR | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) |