Compile Data Set for Download or QSAR

Found 3 hits Enz. Inhib. hit(s) with Target = 'Progesterone receptor' and Ligand = 'BDBM50375816'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Progesterone receptor (Homo sapiens (Human))	BDBM50375816 (CHEMBL407622) Show SMILES Cn1c(ccc1-c1ccc2NC(=O)C3(CCCC3)c2c1)C#N Show InChI InChI=1S/C18H17N3O/c1-21-13(11-19)5-7-16(21)12-4-6-15-14(10-12)18(17(22)20-15)8-2-3-9-18/h4-7,10H,2-3,8-9H2,1H3,(H,20,22)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	8.10	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Displacement of [3H]R5020 from human PR in human T47D cells by whole cell assay				J Med Chem 51: 1861-73 (2008) Article DOI: 10.1021/jm701080t BindingDB Entry DOI: 10.7270/Q2G44R56
					More data for this Ligand-Target Pair
Progesterone receptor (Homo sapiens (Human))	BDBM50375816 (CHEMBL407622) Show SMILES Cn1c(ccc1-c1ccc2NC(=O)C3(CCCC3)c2c1)C#N Show InChI InChI=1S/C18H17N3O/c1-21-13(11-19)5-7-16(21)12-4-6-15-14(10-12)18(17(22)20-15)8-2-3-9-18/h4-7,10H,2-3,8-9H2,1H3,(H,20,22)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	30	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Antagonist activity at human PR expressed in human T47D cells assessed as inhibition of progesterone induced alkaline phosphatase				J Med Chem 51: 1861-73 (2008) Article DOI: 10.1021/jm701080t BindingDB Entry DOI: 10.7270/Q2G44R56
					More data for this Ligand-Target Pair
Progesterone receptor (Homo sapiens (Human))	BDBM50375816 (CHEMBL407622) Show SMILES Cn1c(ccc1-c1ccc2NC(=O)C3(CCCC3)c2c1)C#N Show InChI InChI=1S/C18H17N3O/c1-21-13(11-19)5-7-16(21)12-4-6-15-14(10-12)18(17(22)20-15)8-2-3-9-18/h4-7,10H,2-3,8-9H2,1H3,(H,20,22)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	300	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Agonist activity at human PR expressed in human T47D cells assessed as stimulation of alkaline phosphatase				J Med Chem 51: 1861-73 (2008) Article DOI: 10.1021/jm701080t BindingDB Entry DOI: 10.7270/Q2G44R56
					More data for this Ligand-Target Pair