Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Prolyl 4-hydroxylase subunit alpha-1 (Rattus norvegicus) | BDBM26114 (CHEMBL88972 | pyridine carboxylate, 6b | pyridine-...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents | PubMed | 800 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
ICI Pharmaceuticals Curated by ChEMBL | Assay Description Inhibitory activity against prolyl 4-hydroxylase | J Med Chem 35: 2652-8 (1992) BindingDB Entry DOI: 10.7270/Q28P5ZF9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prolyl 4-hydroxylase subunit alpha-1 (Homo sapiens (Human)) | BDBM26114 (CHEMBL88972 | pyridine carboxylate, 6b | pyridine-...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents | Article PubMed | 2.60E+3 | n/a | n/a | n/a | n/a | n/a | n/a | 7.8 | n/a |
University of Wisconsin-Madison Curated by ChEMBL | Assay Description Inhibition of human human recombinant CP4H1 expressed in Escherichia coli Origami B(DE3) pre-incubated for 2 mins followed by alpha-ketoglutarate add... | Bioorg Med Chem 23: 3081-90 (2015) Article DOI: 10.1016/j.bmc.2015.05.003 BindingDB Entry DOI: 10.7270/Q2N01897 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prolyl 4-hydroxylase subunit alpha-1 (Rattus norvegicus) | BDBM26114 (CHEMBL88972 | pyridine carboxylate, 6b | pyridine-...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents | PubMed | n/a | n/a | 5.18E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
ICI Pharmaceuticals Curated by ChEMBL | Assay Description Compound was evaluated for the inhibition of prolyl 4-hydroxylase | J Med Chem 35: 2652-8 (1992) BindingDB Entry DOI: 10.7270/Q28P5ZF9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prolyl 4-hydroxylase subunit alpha-1 (Homo sapiens (Human)) | BDBM26114 (CHEMBL88972 | pyridine carboxylate, 6b | pyridine-...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents | Article PubMed | n/a | n/a | 1.50E+4 | n/a | n/a | n/a | n/a | 7.8 | n/a |
University of Wisconsin-Madison Curated by ChEMBL | Assay Description Inhibition of human human recombinant CP4H1 expressed in Escherichia coli Origami B(DE3) pre-incubated for 2 mins followed by alpha-ketoglutarate add... | Bioorg Med Chem 23: 3081-90 (2015) Article DOI: 10.1016/j.bmc.2015.05.003 BindingDB Entry DOI: 10.7270/Q2N01897 | |||||||||||
More data for this Ligand-Target Pair |