Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Prostaglandin E synthase 2' and Ligand = 'BDBM181833'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Prostaglandin E synthase 2 (Homo sapiens (Human))	BDBM181833 (US9145380, 36) Show SMILES NS(=O)(=O)c1c(F)cccc1NS(=O)(=O)\C=C\c1ccc(cc1)-c1ccco1 Show InChI InChI=1S/C18H15FN2O5S2/c19-15-3-1-4-16(18(15)28(20,24)25)21-27(22,23)12-10-13-6-8-14(9-7-13)17-5-2-11-26-17/h1-12,21H,(H2,20,24,25)/b12-10+	PDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	57	n/a	n/a	n/a	n/a	6.8	n/a
Astrazeneca AB US Patent					Assay Description A solution of test compound was added to a diluted microsome preparation containing human mPGES-1 and pre-incubated for 15 minutes in potassium phosp...				US Patent US9145380 (2015) BindingDB Entry DOI: 10.7270/Q2XG9PXM
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