Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Prostaglandin E synthase 2 (Homo sapiens (Human)) | BDBM50168766 (3-(1-(4-chlorobenzyl)-5-(2-fluoro-2'-methylbipheny...) | PDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid PDB UniChem Similars | Article PubMed | n/a | n/a | 3 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Frosst Centre for Therapeutic Research Curated by ChEMBL | Assay Description Inhibitory concentration against human prostaglandin E2 synthase (mPGES-1) | Bioorg Med Chem Lett 15: 3352-5 (2005) Article DOI: 10.1016/j.bmcl.2005.05.027 BindingDB Entry DOI: 10.7270/Q21R6Q1X | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin E synthase 2 (Homo sapiens (Human)) | BDBM50168766 (3-(1-(4-chlorobenzyl)-5-(2-fluoro-2'-methylbipheny...) | PDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid PDB UniChem Similars | Article PubMed | n/a | n/a | >1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Frosst Centre for Therapeutic Research Curated by ChEMBL | Assay Description Inhibition of human mPGES2 | Bioorg Med Chem Lett 17: 6816-20 (2008) Article DOI: 10.1016/j.bmcl.2007.10.033 BindingDB Entry DOI: 10.7270/Q25X29RT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin E synthase 2 (Homo sapiens (Human)) | BDBM50168766 (3-(1-(4-chlorobenzyl)-5-(2-fluoro-2'-methylbipheny...) | PDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid PDB UniChem Similars | Article PubMed | n/a | n/a | >1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Frosst Centre for Therapeutic Research Curated by ChEMBL | Assay Description Inhibition of mPGES2 | J Med Chem 51: 4059-67 (2008) Article DOI: 10.1021/jm800197b BindingDB Entry DOI: 10.7270/Q27W6C0K | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin E synthase 2 (Homo sapiens (Human)) | BDBM50168766 (3-(1-(4-chlorobenzyl)-5-(2-fluoro-2'-methylbipheny...) | PDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid PDB UniChem Similars | Article PubMed | n/a | n/a | >1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Frosst Centre for Therapeutic Research Curated by ChEMBL | Assay Description In vitro inhibition against recombinant human mPGES-2 | Bioorg Med Chem Lett 15: 3352-5 (2005) Article DOI: 10.1016/j.bmcl.2005.05.027 BindingDB Entry DOI: 10.7270/Q21R6Q1X | |||||||||||
More data for this Ligand-Target Pair |