Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Prostaglandin E2 receptor EP4 subtype' and Ligand = 'BDBM144431'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Prostaglandin E2 receptor EP4 subtype (Homo sapiens (Human))	BDBM144431 (US8969394, 2) Show SMILES CC(NC(=O)c1sc(Cl)cc1Cc1cccc(Cl)c1)c1ccc(cc1)-c1nn[nH]n1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	2.60	-49.0	n/a	n/a	n/a	n/a	n/a	6.0	25
Merck Frosst Canada Ltd. US Patent					Assay Description Transfected HEK 293(ebna) cells are maintained in culture, harvested and membranes are prepared by differential centrifugation, following lysis of th...				US Patent US8969394 (2015) BindingDB Entry DOI: 10.7270/Q24X56H8
					More data for this Ligand-Target Pair