Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Prostaglandin E2 receptor EP4 subtype (Homo sapiens (Human)) | BDBM50142480 ((E)-7-[(1R,2S,3R)-3-Hydroxy-2-((E)-(S)-3-hydroxy-o...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | 0.800 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Roche Palo Alto Curated by ChEMBL | Assay Description Binding affinity was determined against prostanoid EP4 receptor | Bioorg Med Chem Lett 14: 1655-9 (2004) Article DOI: 10.1016/j.bmcl.2004.01.063 BindingDB Entry DOI: 10.7270/Q2MK6CBC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin E2 receptor EP4 subtype (Homo sapiens (Human)) | BDBM50142480 ((E)-7-[(1R,2S,3R)-3-Hydroxy-2-((E)-(S)-3-hydroxy-o...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | n/a | n/a | n/a | n/a | 6.10 | n/a | n/a | n/a | n/a |
Roche Palo Alto Curated by ChEMBL | Assay Description Agonist activity against recombinant prostanoid EP4 receptor stably transfected in CHO cells | Bioorg Med Chem Lett 14: 1655-9 (2004) Article DOI: 10.1016/j.bmcl.2004.01.063 BindingDB Entry DOI: 10.7270/Q2MK6CBC | |||||||||||
More data for this Ligand-Target Pair |