Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Prostaglandin E2 receptor EP4 subtype' and Ligand = 'BDBM50334140'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Prostaglandin E2 receptor EP4 subtype (Homo sapiens (Human))	BDBM50334140 ((S)-4-(1-(1-(pyridin-3-ylmethyl)indoline-7-carboxa...) Show SMILES C[C@H](NC(=O)c1cccc2CCN(Cc3cccnc3)c12)c1ccc(cc1)C(O)=O |r| Show InChI InChI=1S/C24H23N3O3/c1-16(18-7-9-20(10-8-18)24(29)30)26-23(28)21-6-2-5-19-11-13-27(22(19)21)15-17-4-3-12-25-14-17/h2-10,12,14,16H,11,13,15H2,1H3,(H,26,28)(H,29,30)/t16-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	76	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Frosst Canada Inc. Curated by ChEMBL					Assay Description Displacement of [3H]PGE2 from human prostanoid EP4 receptor expressed in HEK293-EBNA cells after 60 mins by scintillation counting				Bioorg Med Chem Lett 21: 484-7 (2010) Article DOI: 10.1016/j.bmcl.2010.10.106 BindingDB Entry DOI: 10.7270/Q2BZ6695
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP4 subtype (Homo sapiens (Human))	BDBM50334140 ((S)-4-(1-(1-(pyridin-3-ylmethyl)indoline-7-carboxa...) Show SMILES C[C@H](NC(=O)c1cccc2CCN(Cc3cccnc3)c12)c1ccc(cc1)C(O)=O |r| Show InChI InChI=1S/C24H23N3O3/c1-16(18-7-9-20(10-8-18)24(29)30)26-23(28)21-6-2-5-19-11-13-27(22(19)21)15-17-4-3-12-25-14-17/h2-10,12,14,16H,11,13,15H2,1H3,(H,26,28)(H,29,30)/t16-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	258	n/a	n/a	n/a	n/a	n/a	n/a
Merck Frosst Canada Inc. Curated by ChEMBL					Assay Description Antagonist activity at human prostanoid EP4 receptor expressed in HEK293 cells assessed as inhibition of PGE2-induced cAMP accumulation by scintillat...				Bioorg Med Chem Lett 21: 484-7 (2010) Article DOI: 10.1016/j.bmcl.2010.10.106 BindingDB Entry DOI: 10.7270/Q2BZ6695
					More data for this Ligand-Target Pair