Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Prostaglandin E2 receptor EP4 subtype' and Ligand = 'BDBM50334145'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Prostaglandin E2 receptor EP4 subtype (Homo sapiens (Human))	BDBM50334145 ((S)-4-(1-(1-(3-cyanobenzyl)indoline-7-carboxamido)...) Show SMILES C[C@H](NC(=O)c1cccc2CCN(Cc3cccc(c3)C#N)c12)c1ccc(cc1)C(O)=O |r| Show InChI InChI=1S/C26H23N3O3/c1-17(20-8-10-22(11-9-20)26(31)32)28-25(30)23-7-3-6-21-12-13-29(24(21)23)16-19-5-2-4-18(14-19)15-27/h2-11,14,17H,12-13,16H2,1H3,(H,28,30)(H,31,32)/t17-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	7.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Frosst Canada Inc. Curated by ChEMBL					Assay Description Displacement of [3H]PGE2 from human prostanoid EP4 receptor expressed in HEK293-EBNA cells after 60 mins by scintillation counting				Bioorg Med Chem Lett 21: 484-7 (2010) Article DOI: 10.1016/j.bmcl.2010.10.106 BindingDB Entry DOI: 10.7270/Q2BZ6695
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP4 subtype (Homo sapiens (Human))	BDBM50334145 ((S)-4-(1-(1-(3-cyanobenzyl)indoline-7-carboxamido)...) Show SMILES C[C@H](NC(=O)c1cccc2CCN(Cc3cccc(c3)C#N)c12)c1ccc(cc1)C(O)=O |r| Show InChI InChI=1S/C26H23N3O3/c1-17(20-8-10-22(11-9-20)26(31)32)28-25(30)23-7-3-6-21-12-13-29(24(21)23)16-19-5-2-4-18(14-19)15-27/h2-11,14,17H,12-13,16H2,1H3,(H,28,30)(H,31,32)/t17-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	212	n/a	n/a	n/a	n/a	n/a	n/a
Merck Frosst Canada Inc. Curated by ChEMBL					Assay Description Antagonist activity at human prostanoid EP4 receptor expressed in HEK293 cells assessed as inhibition of PGE2-induced cAMP accumulation by scintillat...				Bioorg Med Chem Lett 21: 484-7 (2010) Article DOI: 10.1016/j.bmcl.2010.10.106 BindingDB Entry DOI: 10.7270/Q2BZ6695
					More data for this Ligand-Target Pair