Compile Data Set for Download or QSAR

Found 4 hits Enz. Inhib. hit(s) with Target = 'Prostaglandin E2 receptor EP4 subtype' and Ligand = 'BDBM50335998'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Prostaglandin E2 receptor EP4 subtype (Homo sapiens (Human))	BDBM50335998 (2,3-dichloro-N-(1-(4-(4,9-diethoxy-1-oxo-1H-benzo[...) Show SMILES CCOc1c2CN(C(=O)c2c(OCC)c2ccccc12)c1ccc(CC2(CC2)NC(=O)NS(=O)(=O)c2cccc(Cl)c2Cl)cc1C Show InChI InChI=1S/C34H33Cl2N3O6S/c1-4-44-30-22-9-6-7-10-23(22)31(45-5-2)28-24(30)19-39(32(28)40)26-14-13-21(17-20(26)3)18-34(15-16-34)37-33(41)38-46(42,43)27-12-8-11-25(35)29(27)36/h6-14,17H,4-5,15-16,18-19H2,1-3H3,(H2,37,38,41)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	0.400	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Frosst Centre for Therapeutic Research Curated by ChEMBL					Assay Description Antagonist activity at human EP4 receptor expressed in HEK293 cells assessed as PGE2-induced cAMP accumulation by scintillation proximity assay				Bioorg Med Chem Lett 21: 1041-6 (2011) Article DOI: 10.1016/j.bmcl.2010.12.014 BindingDB Entry DOI: 10.7270/Q2VH5P4H
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP4 subtype (Homo sapiens (Human))	BDBM50335998 (2,3-dichloro-N-(1-(4-(4,9-diethoxy-1-oxo-1H-benzo[...) Show SMILES CCOc1c2CN(C(=O)c2c(OCC)c2ccccc12)c1ccc(CC2(CC2)NC(=O)NS(=O)(=O)c2cccc(Cl)c2Cl)cc1C Show InChI InChI=1S/C34H33Cl2N3O6S/c1-4-44-30-22-9-6-7-10-23(22)31(45-5-2)28-24(30)19-39(32(28)40)26-14-13-21(17-20(26)3)18-34(15-16-34)37-33(41)38-46(42,43)27-12-8-11-25(35)29(27)36/h6-14,17H,4-5,15-16,18-19H2,1-3H3,(H2,37,38,41)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	64	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Frosst Centre for Therapeutic Research Curated by ChEMBL					Assay Description Antagonist activity at human EP4 receptor expressed in HEK293 cells assessed as PGE2-induced cAMP accumulation by scintillation proximity assay in pr...				Bioorg Med Chem Lett 21: 1041-6 (2011) Article DOI: 10.1016/j.bmcl.2010.12.014 BindingDB Entry DOI: 10.7270/Q2VH5P4H
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP4 subtype (Homo sapiens (Human))	BDBM50335998 (2,3-dichloro-N-(1-(4-(4,9-diethoxy-1-oxo-1H-benzo[...) Show SMILES CCOc1c2CN(C(=O)c2c(OCC)c2ccccc12)c1ccc(CC2(CC2)NC(=O)NS(=O)(=O)c2cccc(Cl)c2Cl)cc1C Show InChI InChI=1S/C34H33Cl2N3O6S/c1-4-44-30-22-9-6-7-10-23(22)31(45-5-2)28-24(30)19-39(32(28)40)26-14-13-21(17-20(26)3)18-34(15-16-34)37-33(41)38-46(42,43)27-12-8-11-25(35)29(27)36/h6-14,17H,4-5,15-16,18-19H2,1-3H3,(H2,37,38,41)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
Merck Frosst Centre for Therapeutic Research Curated by ChEMBL					Assay Description Displacement of [3H]PGE2 from human EP4 receptor expressed in HEK293 cells by scintillation counting				Bioorg Med Chem Lett 21: 1041-6 (2011) Article DOI: 10.1016/j.bmcl.2010.12.014 BindingDB Entry DOI: 10.7270/Q2VH5P4H
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP4 subtype (Homo sapiens (Human))	BDBM50335998 (2,3-dichloro-N-(1-(4-(4,9-diethoxy-1-oxo-1H-benzo[...) Show SMILES CCOc1c2CN(C(=O)c2c(OCC)c2ccccc12)c1ccc(CC2(CC2)NC(=O)NS(=O)(=O)c2cccc(Cl)c2Cl)cc1C Show InChI InChI=1S/C34H33Cl2N3O6S/c1-4-44-30-22-9-6-7-10-23(22)31(45-5-2)28-24(30)19-39(32(28)40)26-14-13-21(17-20(26)3)18-34(15-16-34)37-33(41)38-46(42,43)27-12-8-11-25(35)29(27)36/h6-14,17H,4-5,15-16,18-19H2,1-3H3,(H2,37,38,41)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	28	n/a	n/a	n/a	n/a	n/a	n/a
Merck Frosst Centre for Therapeutic Research Curated by ChEMBL					Assay Description Displacement of [3H]PGE2 from human EP4 receptor expressed in HEK293 cells by scintillation counting in presence of 10% human serum				Bioorg Med Chem Lett 21: 1041-6 (2011) Article DOI: 10.1016/j.bmcl.2010.12.014 BindingDB Entry DOI: 10.7270/Q2VH5P4H
					More data for this Ligand-Target Pair