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Found 1 hit Enz. Inhib. hit(s) with Target = 'Prostaglandin-H2 D-isomerase' and Ligand = 'BDBM50009871'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Prostaglandin-H2 D-isomerase


(Mus musculus)		BDBM50009871
PNG
(Benzo[b]thiophen-3-yl-[2-methyl-1-(2-morpholin-4-y...)
Show SMILES Cc1c(C(=O)c2csc3ccccc23)c2ccccc2n1CCN1CCOCC1
Show InChI InChI=1S/C24H24N2O2S/c1-17-23(24(27)20-16-29-22-9-5-3-6-18(20)22)19-7-2-4-8-21(19)26(17)11-10-25-12-14-28-15-13-25/h2-9,16H,10-15H2,1H3
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PC sid
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n/an/a 18n/an/an/an/an/an/a



Sterling Research Group

Curated by ChEMBL


Assay Description
Concentration required to inhibit 50% activity of prostaglandin synthetase was determined in vitro in mouse brain microsomes

J Med Chem 34: 1099-110 (1991)


BindingDB Entry DOI: 10.7270/Q24M955S
More data for this
Ligand-Target Pair