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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Protein Farnesyltransferase (PFT)/farnesyltransferase beta subunit' and Ligand = 'BDBM50060145'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Protein Farnesyltransferase (PFT)/farnesyltransferase beta subunit


(Rattus norvegicus-Rattus norvegicus (rat))
BDBM50060145
PNG
(CHEMBL115669 | [(S)-1-{(4-Benzyloxy-benzyl)-[((S)-...)
Show SMILES C[C@H](CNC(=O)CN(Cc1ccc(OCc2ccccc2)cc1)C(=O)[C@H](Cc1cnc[nH]1)NC(=O)OCc1ccccc1)c1ccccc1
Show InChI InChI=1S/C39H41N5O5/c1-29(33-15-9-4-10-16-33)22-41-37(45)25-44(24-30-17-19-35(20-18-30)48-26-31-11-5-2-6-12-31)38(46)36(21-34-23-40-28-42-34)43-39(47)49-27-32-13-7-3-8-14-32/h2-20,23,28-29,36H,21-22,24-27H2,1H3,(H,40,42)(H,41,45)(H,43,47)/t29-,36+/m1/s1
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 5n/an/an/an/an/an/a



Warner-Lambert Company

Curated by ChEMBL


Assay Description
In vitro inhibition of rat farnesyltransferase.


J Med Chem 40: 3319-22 (1997)


Article DOI: 10.1021/jm970470c
BindingDB Entry DOI: 10.7270/Q2V69HQG
More data for this
Ligand-Target Pair