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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Protein Farnesyltransferase (PFT)/farnesyltransferase beta subunit' and Ligand = 'BDBM50060146'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Protein Farnesyltransferase (PFT)/farnesyltransferase beta subunit


(Rattus norvegicus-Rattus norvegicus (rat))
BDBM50060146
PNG
(CHEMBL407445 | [(S)-1-((4-Benzyloxy-benzyl)-{[(1-p...)
Show SMILES O=C(CN(Cc1ccc(OCc2ccccc2)cc1)C(=O)[C@H](Cc1cnc[nH]1)NC(=O)OCc1ccccc1)NCC1(CC1)c1ccccc1
Show InChI InChI=1S/C40H41N5O5/c46-37(42-28-40(20-21-40)33-14-8-3-9-15-33)25-45(24-30-16-18-35(19-17-30)49-26-31-10-4-1-5-11-31)38(47)36(22-34-23-41-29-43-34)44-39(48)50-27-32-12-6-2-7-13-32/h1-19,23,29,36H,20-22,24-28H2,(H,41,43)(H,42,46)(H,44,48)/t36-/m0/s1
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents

Article
PubMed
n/an/a 7n/an/an/an/an/an/a



Warner-Lambert Company

Curated by ChEMBL


Assay Description
In vitro inhibition of rat farnesyltransferase.


J Med Chem 40: 3319-22 (1997)


Article DOI: 10.1021/jm970470c
BindingDB Entry DOI: 10.7270/Q2V69HQG
More data for this
Ligand-Target Pair