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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Protein Farnesyltransferase (PFT)/farnesyltransferase beta subunit' and Ligand = 'BDBM50060148'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Protein Farnesyltransferase (PFT)/farnesyltransferase beta subunit


(Rattus norvegicus-Rattus norvegicus (rat))
BDBM50060148
PNG
(CHEMBL325331 | [(S)-1-{(4-Benzyloxy-benzyl)-[(2-ph...)
Show SMILES CCCC(CNC(=O)CN(Cc1ccc(OCc2ccccc2)cc1)C(=O)[C@H](Cc1cnc[nH]1)NC(=O)OCc1ccccc1)c1ccccc1
Show InChI InChI=1S/C41H45N5O5/c1-2-12-35(34-17-10-5-11-18-34)24-43-39(47)27-46(26-31-19-21-37(22-20-31)50-28-32-13-6-3-7-14-32)40(48)38(23-36-25-42-30-44-36)45-41(49)51-29-33-15-8-4-9-16-33/h3-11,13-22,25,30,35,38H,2,12,23-24,26-29H2,1H3,(H,42,44)(H,43,47)(H,45,49)/t35?,38-/m0/s1
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents

Article
PubMed
n/an/a 25n/an/an/an/an/an/a



Warner-Lambert Company

Curated by ChEMBL


Assay Description
In vitro inhibition of rat farnesyltransferase.


J Med Chem 40: 3319-22 (1997)


Article DOI: 10.1021/jm970470c
BindingDB Entry DOI: 10.7270/Q2V69HQG
More data for this
Ligand-Target Pair