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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Protein Farnesyltransferase (PFT)' and Ligand = 'BDBM50100300'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Protein Farnesyltransferase (PFT)


(Homo sapiens (Human))
BDBM50100300
PNG
(2-(2,4-Dichloro-phenylsulfanyl)-4-imidazol-1-ylmet...)
Show SMILES Clc1ccc(Sc2cc(Cn3ccnc3)ccc2C#N)c(Cl)c1
Show InChI InChI=1S/C17H11Cl2N3S/c18-14-3-4-16(15(19)8-14)23-17-7-12(1-2-13(17)9-20)10-22-6-5-21-11-22/h1-8,11H,10H2
PDB
MMDB

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n/an/a<1n/an/an/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
Inhibition of rate of incorporation of [3H]-GGPP into a biotinylated peptide corresponding to C-terminus of human Ki-Ras by human geranylgeranyl-tran...


Bioorg Med Chem Lett 11: 1257-60 (2001)


BindingDB Entry DOI: 10.7270/Q2FX78RS
More data for this
Ligand-Target Pair