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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Protein Farnesyltransferase (PFT)' and Ligand = 'BDBM50126320'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Protein Farnesyltransferase (PFT)


(Homo sapiens (Human))
BDBM50126320
PNG
(1-{[(4-Cyano-phenyl)-(3-methyl-3H-imidazol-4-yl)-m...)
Show SMILES Cn1cncc1C(NN1CCC(C#N)=C(C1)c1cccc2ccccc12)c1ccc(cc1)C#N |c:14|
Show InChI InChI=1S/C28H24N6/c1-33-19-31-17-27(33)28(22-11-9-20(15-29)10-12-22)32-34-14-13-23(16-30)26(18-34)25-8-4-6-21-5-2-3-7-24(21)25/h2-12,17,19,28,32H,13-14,18H2,1H3
PDB
MMDB

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n/an/a 0.5n/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
In vitro inhibition of farnesyltransferase


Bioorg Med Chem Lett 13: 1363-6 (2003)


BindingDB Entry DOI: 10.7270/Q24B30PD
More data for this
Ligand-Target Pair