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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Protein Farnesyltransferase (PFT)' and Ligand = 'BDBM50127311'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Protein Farnesyltransferase (PFT)


(Bos taurus (bovine))
BDBM50127311
PNG
(5-[(4-Cyano-phenyl)-(3-methyl-3H-imidazol-4-yl)-me...)
Show SMILES Cn1cncc1C(OCc1ccc(nc1-c1ccc(OC(F)(F)F)cc1)C#N)c1ccc(cc1)C#N
Show InChI InChI=1S/C26H18F3N5O2/c1-34-16-32-14-23(34)25(19-4-2-17(12-30)3-5-19)35-15-20-6-9-21(13-31)33-24(20)18-7-10-22(11-8-18)36-26(27,28)29/h2-11,14,16,25H,15H2,1H3
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
PubMed
n/an/a 0.510n/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Inhibition of transfer of [3H]-FPP to biotin K-ras peptide (KKSKTKCVIM) catalyzed by bovine FTase


Bioorg Med Chem Lett 13: 1571-4 (2003)


BindingDB Entry DOI: 10.7270/Q27080TK
More data for this
Ligand-Target Pair