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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Protein Farnesyltransferase (PFT)' and Ligand = 'BDBM50134308'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Protein Farnesyltransferase (PFT)


(Homo sapiens (Human))
BDBM50134308
PNG
(3-Benzyldisulfanyl-2-methyl-2,3-dihydro-pyrazino[1...)
Show SMILES CN1C(SSCc2ccccc2)C(=O)n2c(cc3ccccc23)C1=O
Show InChI InChI=1S/C19H16N2O2S2/c1-20-17(22)16-11-14-9-5-6-10-15(14)21(16)18(23)19(20)25-24-12-13-7-3-2-4-8-13/h2-11,19H,12H2,1H3
PDB
MMDB

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n/an/a>1.00E+5n/an/an/an/an/an/a



Imperial College of Science

Curated by ChEMBL


Assay Description
Inhibition of [3H]-FPP incorporation into recombinant human Ha-Ras-CVLS by farnesyl transferase


Bioorg Med Chem Lett 13: 3661-3 (2003)


BindingDB Entry DOI: 10.7270/Q2CF9PHX
More data for this
Ligand-Target Pair