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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Protein Kinase C, alpha' and Ligand = 'BDBM50133240'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Protein Kinase C, alpha


(Bos taurus (bovine))
BDBM50133240
PNG
(CHEMBL135611 | Decanedioic acid ((2S,5S)-5-hydroxy...)
Show SMILES CC(C)[C@@H]1N(C)c2ccc(NC(=O)CCCCCCCCC(=O)Nc3ccc(O)c4ccccc34)cc2C[C@@H](CO)NC1=O
Show InChI InChI=1S/C35H46N4O5/c1-23(2)34-35(44)37-26(22-40)21-24-20-25(16-18-30(24)39(34)3)36-32(42)14-8-6-4-5-7-9-15-33(43)38-29-17-19-31(41)28-13-11-10-12-27(28)29/h10-13,16-20,23,26,34,40-41H,4-9,14-15,21-22H2,1-3H3,(H,36,42)(H,37,44)(H,38,43)/t26-,34-/m0/s1
PDB
MMDB

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PC cid
PC sid
UniChem
Article
PubMed
57n/an/an/an/an/an/an/an/a



Georgetown University Medical Center

Curated by ChEMBL


Assay Description
Tested for ability to displace [20e3] phorbol 12,13- dibutyrate binding from recombinant bovine Protein kinase C alpha in presence of [Ca2+]


J Med Chem 46: 4196-204 (2003)


Article DOI: 10.1021/jm0302041
BindingDB Entry DOI: 10.7270/Q2GF0SX2
More data for this
Ligand-Target Pair