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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Protein Kinase C, alpha' and Ligand = 'BDBM50133246'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Protein Kinase C, alpha


(Bos taurus (bovine))
BDBM50133246
PNG
(CHEMBL335486 | Hexanedioic acid [(S)-5-hydroxymeth...)
Show SMILES CC(C)[C@@H]1N(C)c2ccc(NC(=O)CCCCC(=O)Nc3ccc4C[C@@H](CO)NC(=O)[C@H](C(C)C)N(C)c4c3)cc2C[C@@H](CO)NC1=O
Show InChI InChI=1S/C36H52N6O6/c1-21(2)33-35(47)40-28(20-44)17-24-16-25(13-14-29(24)41(33)5)37-31(45)9-7-8-10-32(46)38-26-12-11-23-15-27(19-43)39-36(48)34(22(3)4)42(6)30(23)18-26/h11-14,16,18,21-22,27-28,33-34,43-44H,7-10,15,17,19-20H2,1-6H3,(H,37,45)(H,38,46)(H,39,48)(H,40,47)/t27-,28-,33-,34-/m0/s1
PDB
MMDB

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PC cid
PC sid
UniChem
Article
PubMed
320n/an/an/an/an/an/an/an/a



Georgetown University Medical Center

Curated by ChEMBL


Assay Description
Tested for ability to displace [20e3] phorbol 12,13- dibutyrate binding from recombinant bovine Protein kinase C alpha in presence of [Ca2+]


J Med Chem 46: 4196-204 (2003)


Article DOI: 10.1021/jm0302041
BindingDB Entry DOI: 10.7270/Q2GF0SX2
More data for this
Ligand-Target Pair