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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Protein Kinase C' and Ligand = 'BDBM2645'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Protein Kinase C


(Rattus norvegicus (rat))
BDBM2645
PNG
((Phenylindolyl)maleimide deriv. 67 | 3-(3-methoxyp...)
Show SMILES COc1cccc(c1)C1=C(C(=O)NC1=O)c1cn(C)c2ccccc12 |t:9|
Show InChI InChI=1S/C20H16N2O3/c1-22-11-15(14-8-3-4-9-16(14)22)18-17(19(23)21-20(18)24)12-6-5-7-13(10-12)25-2/h3-11H,1-2H3,(H,21,23,24)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 8.00E+3n/an/an/an/an/an/a



Roche Products Limited



Assay Description
The activity of PKC, activated by phosphatidylerine and Ca2+, is measured by its ability to transfer phosphate from [gamma-32P]ATP to lysine-rich his...


J Med Chem 35: 177-84 (1992)


Article DOI: 10.1016/j.bmc.2005.03.050
BindingDB Entry DOI: 10.7270/Q2K64G8V
More data for this
Ligand-Target Pair