Compile Data Set for Download or QSAR

Found 4 hits Enz. Inhib. hit(s) with Target = 'Protein Wnt-3a' and Ligand = 'BDBM300610'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Protein Wnt-3a (Homo sapiens (Human))	BDBM300610 (N-[6-(3,5- difluorophenyl)pyridin-3-yl]-3- ({(2R*)...) Show SMILES CC(N1C[C@@H]2C[C@H]1CO2)C(=O)Nc1cc(ccc1OC(F)(F)F)C(=O)Nc1ccc(nc1)-c1cc(F)cc(F)c1 |r| Show InChI InChI=1S/C27H23F5N4O4/c1-14(36-12-21-10-20(36)13-39-21)25(37)35-23-8-15(2-5-24(23)40-27(30,31)32)26(38)34-19-3-4-22(33-11-19)16-6-17(28)9-18(29)7-16/h2-9,11,14,20-21H,10,12-13H2,1H3,(H,34,38)(H,35,37)/t14?,20-,21-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	53	n/a	n/a	n/a	n/a	n/a	n/a
BAYER PHARMA AKTIENGESELLSCHAFT US Patent					Assay Description In preparation of the assay, the two cell lines were plated 24 hours before at 10000 cells per well of a 384 micro titre plate (MTP) in 30 μL gr...				US Patent US10130633 (2018) BindingDB Entry DOI: 10.7270/Q2FN188G
					More data for this Ligand-Target Pair
Protein Wnt-3a (Homo sapiens (Human))	BDBM300610 (N-[6-(3,5- difluorophenyl)pyridin-3-yl]-3- ({(2R*)...) Show SMILES CC(N1C[C@@H]2C[C@H]1CO2)C(=O)Nc1cc(ccc1OC(F)(F)F)C(=O)Nc1ccc(nc1)-c1cc(F)cc(F)c1 |r| Show InChI InChI=1S/C27H23F5N4O4/c1-14(36-12-21-10-20(36)13-39-21)25(37)35-23-8-15(2-5-24(23)40-27(30,31)32)26(38)34-19-3-4-22(33-11-19)16-6-17(28)9-18(29)7-16/h2-9,11,14,20-21H,10,12-13H2,1H3,(H,34,38)(H,35,37)/t14?,20-,21-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	148	n/a	n/a	n/a	n/a	n/a	n/a
BAYER PHARMA AKTIENGESELLSCHAFT US Patent					Assay Description In preparation of the assay, the two cell lines were plated 24 hours before at 10000 cells per well of a 384 micro titre plate (MTP) in 30 μL gr...				US Patent US10130633 (2018) BindingDB Entry DOI: 10.7270/Q2FN188G
					More data for this Ligand-Target Pair
Protein Wnt-3a (Homo sapiens (Human))	BDBM300610 (N-[6-(3,5- difluorophenyl)pyridin-3-yl]-3- ({(2R*)...) Show SMILES CC(N1C[C@@H]2C[C@H]1CO2)C(=O)Nc1cc(ccc1OC(F)(F)F)C(=O)Nc1ccc(nc1)-c1cc(F)cc(F)c1 |r| Show InChI InChI=1S/C27H23F5N4O4/c1-14(36-12-21-10-20(36)13-39-21)25(37)35-23-8-15(2-5-24(23)40-27(30,31)32)26(38)34-19-3-4-22(33-11-19)16-6-17(28)9-18(29)7-16/h2-9,11,14,20-21H,10,12-13H2,1H3,(H,34,38)(H,35,37)/t14?,20-,21-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	9.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
BAYER PHARMA AKTIENGESELLSCHAFT US Patent					Assay Description In preparation of the assay, the two cell lines were plated 24 hours before at 10000 cells per well of a 384 micro titre plate (MTP) in 30 μL gr...				US Patent US10130633 (2018) BindingDB Entry DOI: 10.7270/Q2FN188G
					More data for this Ligand-Target Pair
Protein Wnt-3a (Homo sapiens (Human))	BDBM300610 (N-[6-(3,5- difluorophenyl)pyridin-3-yl]-3- ({(2R*)...) Show SMILES CC(N1C[C@@H]2C[C@H]1CO2)C(=O)Nc1cc(ccc1OC(F)(F)F)C(=O)Nc1ccc(nc1)-c1cc(F)cc(F)c1 |r| Show InChI InChI=1S/C27H23F5N4O4/c1-14(36-12-21-10-20(36)13-39-21)25(37)35-23-8-15(2-5-24(23)40-27(30,31)32)26(38)34-19-3-4-22(33-11-19)16-6-17(28)9-18(29)7-16/h2-9,11,14,20-21H,10,12-13H2,1H3,(H,34,38)(H,35,37)/t14?,20-,21-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
BAYER PHARMA AKTIENGESELLSCHAFT US Patent					Assay Description In preparation of the assay, the two cell lines were plated 24 hours before at 10000 cells per well of a 384 micro titre plate (MTP) in 30 μL gr...				US Patent US10130633 (2018) BindingDB Entry DOI: 10.7270/Q2FN188G
					More data for this Ligand-Target Pair