Compile Data Set for Download or QSAR

Found 4 hits Enz. Inhib. hit(s) with Target = 'Protein arginine N-methyltransferase 3' and Ligand = 'BDBM50247359'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Protein arginine N-methyltransferase 3 (Homo sapiens)	BDBM50247359 (CHEMBL4062783) Show SMILES FC1(F)CN(CC1(F)F)C(=O)CNC(=O)Nc1ccc2cnccc2c1 Show InChI InChI=1S/C16H14F4N4O2/c17-15(18)8-24(9-16(15,19)20)13(25)7-22-14(26)23-12-2-1-11-6-21-4-3-10(11)5-12/h1-6H,7-9H2,(H2,22,23,26)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	24	n/a	n/a	n/a	n/a	n/a	n/a
Icahn School of Medicine at Mount Sinai Curated by ChEMBL					Assay Description Inhibition of PRMT3 (unknown origin) using C-terminally biotinylated histone H4 as substrate in presence of [3H]S-adenosylmethionine by scintillation...				J Med Chem 61: 1204-1217 (2018) Article DOI: 10.1021/acs.jmedchem.7b01674 BindingDB Entry DOI: 10.7270/Q24J0HK6
					More data for this Ligand-Target Pair
Protein arginine N-methyltransferase 3 (Homo sapiens)	BDBM50247359 (CHEMBL4062783) Show SMILES FC1(F)CN(CC1(F)F)C(=O)CNC(=O)Nc1ccc2cnccc2c1 Show InChI InChI=1S/C16H14F4N4O2/c17-15(18)8-24(9-16(15,19)20)13(25)7-22-14(26)23-12-2-1-11-6-21-4-3-10(11)5-12/h1-6H,7-9H2,(H2,22,23,26)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	240	n/a	n/a	n/a	n/a	n/a	n/a
Icahn School of Medicine at Mount Sinai Curated by ChEMBL					Assay Description Inhibition of FLAG-tagged wild type human PRMT3 expressed in HEK293 cells assessed as decrease in exogenous H4R3 dimethylation level using GFP-tagged...				J Med Chem 61: 1204-1217 (2018) Article DOI: 10.1021/acs.jmedchem.7b01674 BindingDB Entry DOI: 10.7270/Q24J0HK6
					More data for this Ligand-Target Pair
Protein arginine N-methyltransferase 3 (Homo sapiens)	BDBM50247359 (CHEMBL4062783) Show SMILES FC1(F)CN(CC1(F)F)C(=O)CNC(=O)Nc1ccc2cnccc2c1 Show InChI InChI=1S/C16H14F4N4O2/c17-15(18)8-24(9-16(15,19)20)13(25)7-22-14(26)23-12-2-1-11-6-21-4-3-10(11)5-12/h1-6H,7-9H2,(H2,22,23,26)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	2.70E+3	n/a	n/a	n/a	n/a
Icahn School of Medicine at Mount Sinai Curated by ChEMBL					Assay Description Binding affinity to beta galactosidase fused human PRMT3 (211 to 531 residues) expressed in human A549 cells after 6 hrs by InCELL hunter assay				J Med Chem 61: 1204-1217 (2018) Article DOI: 10.1021/acs.jmedchem.7b01674 BindingDB Entry DOI: 10.7270/Q24J0HK6
					More data for this Ligand-Target Pair
Protein arginine N-methyltransferase 3 (Homo sapiens)	BDBM50247359 (CHEMBL4062783) Show SMILES FC1(F)CN(CC1(F)F)C(=O)CNC(=O)Nc1ccc2cnccc2c1 Show InChI InChI=1S/C16H14F4N4O2/c17-15(18)8-24(9-16(15,19)20)13(25)7-22-14(26)23-12-2-1-11-6-21-4-3-10(11)5-12/h1-6H,7-9H2,(H2,22,23,26)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	3.10E+3	n/a	n/a	n/a	n/a
Icahn School of Medicine at Mount Sinai Curated by ChEMBL					Assay Description Binding affinity to beta galactosidase fused human PRMT3 (211 to 531 residues) expressed in human HEK293 cells after 6 hrs by InCELL hunter assay				J Med Chem 61: 1204-1217 (2018) Article DOI: 10.1021/acs.jmedchem.7b01674 BindingDB Entry DOI: 10.7270/Q24J0HK6
					More data for this Ligand-Target Pair