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Found 1 hit Enz. Inhib. hit(s) with Target = 'Protein arginine N-methyltransferase 3' and Ligand = 'BDBM50247362'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Protein arginine N-methyltransferase 3


(Homo sapiens)		BDBM50247362
PNG
(CHEMBL4061085)
Show SMILES O=C(NCC(=O)N1C2CCC1CCC2)Nc1ccc2cnccc2c1 |TLB:4:6:8.9:13.12.11|
Show InChI InChI=1S/C19H22N4O2/c24-18(23-16-2-1-3-17(23)7-6-16)12-21-19(25)22-15-5-4-14-11-20-9-8-13(14)10-15/h4-5,8-11,16-17H,1-3,6-7,12H2,(H2,21,22,25)
PDB

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PC cid
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Similars
Article
PubMed
n/an/a 22n/an/an/an/an/an/a



Icahn School of Medicine at Mount Sinai

Curated by ChEMBL


Assay Description
Inhibition of PRMT3 (unknown origin) using C-terminally biotinylated histone H4 as substrate in presence of [3H]S-adenosylmethionine by scintillation...

J Med Chem 61: 1204-1217 (2018)


Article DOI: 10.1021/acs.jmedchem.7b01674
BindingDB Entry DOI: 10.7270/Q24J0HK6
More data for this
Ligand-Target Pair