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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Protein arginine N-methyltransferase 3' and Ligand = 'BDBM50247363'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Protein arginine N-methyltransferase 3


(Homo sapiens)		BDBM50247363
PNG
(CHEMBL4082966)
Show SMILES O=C(NCC(=O)N1C2CCC1CC2)Nc1ccc2cnccc2c1 |TLB:4:6:8.9:11.12|
Show InChI InChI=1S/C18H20N4O2/c23-17(22-15-3-4-16(22)6-5-15)11-20-18(24)21-14-2-1-13-10-19-8-7-12(13)9-14/h1-2,7-10,15-16H,3-6,11H2,(H2,20,21,24)
PDB

UniProtKB/SwissProt

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PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 46n/an/an/an/an/an/a



Icahn School of Medicine at Mount Sinai

Curated by ChEMBL


Assay Description
Inhibition of PRMT3 (unknown origin) using C-terminally biotinylated histone H4 as substrate in presence of [3H]S-adenosylmethionine by scintillation...

J Med Chem 61: 1204-1217 (2018)


Article DOI: 10.1021/acs.jmedchem.7b01674
BindingDB Entry DOI: 10.7270/Q24J0HK6
More data for this
Ligand-Target Pair