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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Protein arginine N-methyltransferase 5' and Ligand = 'BDBM337025'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Protein arginine N-methyltransferase 5


(Homo sapiens (Human))		BDBM337025
PNG
(US9745291, Compound 71 | US9765068, Compound 71)
Show SMILES CN1CCC(CC1)n1ncc2ccc(OCC(=O)NCC(O)CN3CCc4ccccc4C3)cc12
Show InChI InChI=1S/C27H35N5O3/c1-30-11-9-23(10-12-30)32-26-14-25(7-6-21(26)15-29-32)35-19-27(34)28-16-24(33)18-31-13-8-20-4-2-3-5-22(20)17-31/h2-7,14-15,23-24,33H,8-13,16-19H2,1H3,(H,28,34)
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a<100n/an/an/an/an/an/a



Epizyme, Inc.

US Patent


Assay Description
Molecular Biology: Full-length human PRMT5 (NM_006109.3) transcript variant 1 clone was amplified from a fetal brain cDNA library, incorporating flan...

US Patent US9765068 (2017)


BindingDB Entry DOI: 10.7270/Q2959KN3
More data for this
Ligand-Target Pair