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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Protein arginine N-methyltransferase 6' and Ligand = 'BDBM50158372'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Protein arginine N-methyltransferase 6


(Homo sapiens (Human))
BDBM50158372
PNG
(CHEMBL3779956)
Show SMILES CN(C)Cc1ccc(CSCCN)o1
Show InChI InChI=1S/C10H18N2OS/c1-12(2)7-9-3-4-10(13-9)8-14-6-5-11/h3-4H,5-8,11H2,1-2H3
PDB

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CHEMBL
MCE
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 7.20E+4n/an/an/an/an/an/a



University of Toronto

Curated by ChEMBL


Assay Description
Inhibition of N-terminal hexa-His tagged human PRMT6 expressed in Sf9 cells using 24 residues of biotin labelled histone4 substrate and tritiated 3H-...


J Med Chem 59: 1176-83 (2016)


Article DOI: 10.1021/acs.jmedchem.5b01772
BindingDB Entry DOI: 10.7270/Q2SF2Z11
More data for this
Ligand-Target Pair