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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Protein arginine N-methyltransferase 8' and Ligand = 'BDBM50194758'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Protein arginine N-methyltransferase 8


(Homo sapiens (Human))
BDBM50194758
PNG
(CHEMBL3970878)
Show SMILES CNCCN1CCC(CC1)OCc1cccc(c1)-c1ccccc1
Show InChI InChI=1S/C21H28N2O/c1-22-12-15-23-13-10-21(11-14-23)24-17-18-6-5-9-20(16-18)19-7-3-2-4-8-19/h2-9,16,21-22H,10-15,17H2,1H3
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 573n/an/an/an/an/an/a



Icahn School of Medicine at Mount Sinai

Curated by ChEMBL


Assay Description
Inhibition of PRMT8 (unknown origin) assessed as inhibition of methylation activity measured after 3 hrs using [3H]-SAM by scintillation proximity as...


J Med Chem 59: 9124-9139 (2016)


Article DOI: 10.1021/acs.jmedchem.6b01033
BindingDB Entry DOI: 10.7270/Q2028TGJ
More data for this
Ligand-Target Pair