new BindingDB logo
myBDB logout
Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Protein kinase B (Akt 1)' and Ligand = 'BDBM16796'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Protein kinase B (Akt 1)


(Homo sapiens (Human))
BDBM16796
PNG
(3-[(2S)-2-amino-3-phenylpropoxy]-5-[3-(1-methyl-1H...)
Show SMILES Cn1cccc1-c1n[nH]c2cnc(cc12)-c1cncc(OC[C@@H](N)Cc2ccccc2)c1 |r|
Show InChI InChI=1S/C25H24N6O/c1-31-9-5-8-24(31)25-21-12-22(28-15-23(21)29-30-25)18-11-20(14-27-13-18)32-16-19(26)10-17-6-3-2-4-7-17/h2-9,11-15,19H,10,16,26H2,1H3,(H,29,30)/t19-/m0/s1
PDB
MMDB

B.MOAD
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 228n/an/an/an/a7.522



Abbott Laboratories



Assay Description
The kinase assay uses His-Akt1 and a biotinylated peptide as substrate. The biotinylated peptides were immobilized on streptavidin-coated FLASH plat...


Bioorg Med Chem 15: 2441-52 (2007)


Article DOI: 10.1016/j.bmc.2007.01.010
BindingDB Entry DOI: 10.7270/Q26Q1VGQ
More data for this
Ligand-Target Pair