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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Protein kinase C alpha type' and Ligand = 'BDBM50184387'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Protein kinase C alpha type


(Homo sapiens (Human))
BDBM50184387
PNG
(5-(hydroxymethyl)-5-(pivaloyloxymethyl)-3,3-bis(3-...)
Show SMILES [#6]\[#6](-[#6])=[#6]/[#6]C1([#6]\[#6]=[#6](\[#6])-[#6])[#6]C([#6]-[#8])([#6]-[#8]-[#6](=O)C([#6])([#6])[#6])[#8]-[#6]1=O
Show InChI InChI=1S/C21H34O5/c1-15(2)8-10-20(11-9-16(3)4)12-21(13-22,26-18(20)24)14-25-17(23)19(5,6)7/h8-9,22H,10-14H2,1-7H3
PDB
MMDB

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UniProtKB/SwissProt

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PC cid
PC sid
UniChem
Article
PubMed
2.10E+3n/an/an/an/an/an/an/an/a



Research Institute of Pharmaceutical Sciences

Curated by ChEMBL


Assay Description
Displacement of [20-3H]PDBu from recombinant PKC alpha in presence of phosphatidylserine


J Med Chem 49: 2028-36 (2006)


Article DOI: 10.1021/jm0509391
BindingDB Entry DOI: 10.7270/Q27D2TQ1
More data for this
Ligand-Target Pair