BindingDB logo
myBDB logout
Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Protein phosphatase 1D' and Ligand = 'BDBM50118477'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Protein phosphatase 1D


(Homo sapiens (Human))		BDBM50118477
PNG
(CHEMBL3613748)
Show SMILES [H][C@]12C[C@@H](C[C@@](C)(C(O)=O)[C@]1([H])CCC[C@H]2O[Si](CC)(CC)CC)O[Si](C)(C)C(C)(C)C |r|
Show InChI InChI=1S/C24H48O4Si2/c1-10-30(11-2,12-3)28-21-15-13-14-20-19(21)16-18(17-24(20,7)22(25)26)27-29(8,9)23(4,5)6/h18-21H,10-17H2,1-9H3,(H,25,26)/t18-,19-,20+,21+,24+/m0/s1
KEGG

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents

Similars
Article
PubMed
 228n/an/an/an/an/an/an/an/a



Hokkaido University

Curated by ChEMBL


Assay Description
Non-competitive inhibition of His-tagged PPM1D (1 to 420 residues) (unknown origin) expressed in Escherichia coli BL21 (DE3) pLysS cells using Ac-VEP...

Bioorg Med Chem 23: 6246-9 (2015)


Article DOI: 10.1016/j.bmc.2015.08.042
BindingDB Entry DOI: 10.7270/Q26975C7
More data for this
Ligand-Target Pair
Protein phosphatase 1D


(Homo sapiens (Human))		BDBM50118477
PNG
(CHEMBL3613748)
Show SMILES [H][C@]12C[C@@H](C[C@@](C)(C(O)=O)[C@]1([H])CCC[C@H]2O[Si](CC)(CC)CC)O[Si](C)(C)C(C)(C)C |r|
Show InChI InChI=1S/C24H48O4Si2/c1-10-30(11-2,12-3)28-21-15-13-14-20-19(21)16-18(17-24(20,7)22(25)26)27-29(8,9)23(4,5)6/h18-21H,10-17H2,1-9H3,(H,25,26)/t18-,19-,20+,21+,24+/m0/s1
KEGG

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents

Similars
Article
PubMed
n/an/a 110n/an/an/an/an/an/a



Hokkaido University

Curated by ChEMBL


Assay Description
Inhibition of His-tagged PPM1D (1 to 420 residues) (unknown origin) expressed in Escherichia coli BL21 (DE3) pLysS cells using Ac-VEPPLS(P)QETFSDLW-N...

Bioorg Med Chem 23: 6246-9 (2015)


Article DOI: 10.1016/j.bmc.2015.08.042
BindingDB Entry DOI: 10.7270/Q26975C7
More data for this
Ligand-Target Pair