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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Protein-tyrosine kinase 2-beta' and Ligand = 'BDBM50402995'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Protein-tyrosine kinase 2-beta


(Mus musculus)
BDBM50402995
PNG
(CHEMBL2207436)
Show SMILES Cc1ccc(cc1)-n1nc(cc1NC(=O)Nc1cc(n[nH]1)-c1ccc(=O)[nH]n1)C(C)(C)C
Show InChI InChI=1S/C22H24N8O2/c1-13-5-7-14(8-6-13)30-19(12-17(29-30)22(2,3)4)24-21(32)23-18-11-16(26-27-18)15-9-10-20(31)28-25-15/h5-12H,1-4H3,(H,28,31)(H3,23,24,26,27,32)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 3.60E+3n/an/an/an/an/an/a



Pfizer Inc.

Curated by ChEMBL


Assay Description
Inhibition of PYK2 in mouse NIH-3T3 cells by LI-COR assay


Bioorg Med Chem Lett 22: 7523-9 (2012)


Article DOI: 10.1016/j.bmcl.2012.10.039
BindingDB Entry DOI: 10.7270/Q2319X2C
More data for this
Ligand-Target Pair