Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Protein-tyrosine kinase 2-beta' and Ligand = 'BDBM50403003'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Protein-tyrosine kinase 2-beta (Homo sapiens (Human))	BDBM50403003 (CHEMBL2207823) Show SMILES Cc1ccc(cc1)-n1nc(cc1NC(=O)Nc1cccc2cc([nH]c12)C(=O)N1CCCC1)C(C)(C)C Show InChI InChI=1S/C28H32N6O2/c1-18-10-12-20(13-11-18)34-24(17-23(32-34)28(2,3)4)31-27(36)30-21-9-7-8-19-16-22(29-25(19)21)26(35)33-14-5-6-15-33/h7-13,16-17,29H,5-6,14-15H2,1-4H3,(H2,30,31,36)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	31	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Inhibition of human recombinant C-terminal His-tagged PYK2 using ATP as substrate incubated for 1 hr prior to substrate addition				Bioorg Med Chem Lett 22: 7523-9 (2012) Article DOI: 10.1016/j.bmcl.2012.10.039 BindingDB Entry DOI: 10.7270/Q2319X2C
					More data for this Ligand-Target Pair
Protein-tyrosine kinase 2-beta (Mus musculus)	BDBM50403003 (CHEMBL2207823) Show SMILES Cc1ccc(cc1)-n1nc(cc1NC(=O)Nc1cccc2cc([nH]c12)C(=O)N1CCCC1)C(C)(C)C Show InChI InChI=1S/C28H32N6O2/c1-18-10-12-20(13-11-18)34-24(17-23(32-34)28(2,3)4)31-27(36)30-21-9-7-8-19-16-22(29-25(19)21)26(35)33-14-5-6-15-33/h7-13,16-17,29H,5-6,14-15H2,1-4H3,(H2,30,31,36)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	265	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Inhibition of PYK2 in mouse NIH-3T3 cells by LI-COR assay				Bioorg Med Chem Lett 22: 7523-9 (2012) Article DOI: 10.1016/j.bmcl.2012.10.039 BindingDB Entry DOI: 10.7270/Q2319X2C
					More data for this Ligand-Target Pair