BindingDB PrimarySearch

Found 3 hits Enz. Inhib. hit(s) with Target = 'Prothrombin' and Ligand = 'BDBM50003742'
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Prothrombin (Homo sapiens (Human))	BDBM50003742 ((Lactone1)N-[4-(6-Methylene-2-oxo-tetrahydro-pyran...) Show SMILES NC(=N)NCc1ccc(cc1)C1CCC(=C)OC1=O Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	3.79E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Illinois Curated by ChEMBL					Assay Description Compound was tested for its binding affinity against the enzyme thrombin				J Med Chem 35: 4297-305 (1992) BindingDB Entry DOI: 10.7270/Q2TD9W9D
University of Illinois Curated by ChEMBL					More data for this Ligand-Target Pair
Prothrombin (Homo sapiens (Human))	BDBM50003742 ((Lactone1)N-[4-(6-Methylene-2-oxo-tetrahydro-pyran...) Show SMILES NC(=N)NCc1ccc(cc1)C1CCC(=C)OC1=O Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars		n/a	n/a	n/a	n/a	n/a	0.000100	n/a	n/a	n/a
TBA					Assay Description Rate constant of deacylation for thrombin				Citation and Details BindingDB Entry DOI: 10.7270/Q25M67W6
TBA					More data for this Ligand-Target Pair
Prothrombin (Homo sapiens (Human))	BDBM50003742 ((Lactone1)N-[4-(6-Methylene-2-oxo-tetrahydro-pyran...) Show SMILES NC(=N)NCc1ccc(cc1)C1CCC(=C)OC1=O Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	n/a	0.000100	n/a	n/a	n/a
University of Illinois Curated by ChEMBL					Assay Description Compound was tested for the rate constant of deacylation against thrombin				J Med Chem 35: 4297-305 (1992) BindingDB Entry DOI: 10.7270/Q2TD9W9D
University of Illinois Curated by ChEMBL					More data for this Ligand-Target Pair